Sleep research article

Amygdala-putamen connectivity links gratitude to greater well-being.

2026-01-01 · arXiv: 10.1080/19585969.2026.2653597

Authors: Liu G , Yang Y , Wang F , Kong F , Peng K , Sui J

One-line summary

A sleep science research article on Amygdala-putamen connectivity links gratitude to greater well-being..

Sleep health notes

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中文解读

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Original abstract

<h4>Introduction</h4>Gratitude plays a crucial role in promoting affective well-being, yet the neural mechanisms underlying their relationship remains unclear. Given the central role of the nucleus accumbens (NAcc) and amygdala in emotion and reward processing, this study investigated whether resting-state functional connectivity (RSFC) of these subcortical regions correlates with trait gratitude and mediates its association with affective well-being.<h4>Methods</h4>Resting-state fMRI data were collected from 363 young adults. Seed-based connectivity analyses identified NAcc and amygdala connectivity patterns associated with trait gratitude. Mediation analyses tested whether these patterns explained the association between gratitude and affective well-being.<h4>Results</h4>Trait gratitude was linked to stronger connectivity between the left NAcc and dorsomedial prefrontal cortex and left posterior superior temporal sulcus; between the right NAcc and left dorsolateral prefrontal cortex (DLPFC), right inferior temporal gyrus and bilateral fusiform; and between the right amygdala and right DLPFC, superior temporal gyrus, cerebellum, and putamen. Critically, the right amygdala-putamen connectivity mediated the relationship between gratitude and positive affective well-being.<h4>Conclusions</h4>The right amygdala-putamen RSFC links gratitude to greater affective well-being. This finding identifies a specific subcortical pathway through which grateful dispositions translate into emotional benefit and suggests a potential target for interventions aimed at improving mental health.

6.0App value
8.0Research quality
7.0Wellness relevance

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