Sleep research article
Comparison of liver T1 estimates generated by breath-hold 3D FSPGR and free-breathing 3D radial stack-of-stars FSPGR variable flip angle T1 mapping sequences.
Authors: Xu H , Hou Z , Zhang M , Guo R , Zhang J , Fu G , Wen Q , Li Z , Tao F , Yang S
One-line summary
A sleep science research article on Comparison of liver T1 estimates generated by breath-hold 3D FSPGR and free-breathing 3D radial stack-of-stars FSPGR variable flip angle T1 mapping sequences..
Sleep health notes
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中文解读
中文解读待补充：本站会优先为失眠研究、睡眠质量改善、昼夜节律等高价值睡眠研究添加中文说明。
Original abstract
<h4>Objective</h4>To evaluate the feasibility of using the free-breathing (FB) radial stack-of-stars fast spoiled gradient recalled-echo (FSPGR) sequence as an alternative to the conventional breath-hold (BH) FSPGR sequence for hepatic T1 mapping across the clinical range of body mass index (BMI).<h4>Methods</h4>From 07/2024 to 10/2024, 75 participants who underwent both FB and BH FSPGR were analyzed. Participants were stratified into 3 BMI groups. BH IDEAL IQ was also collected to enable PDFF to be evaluated. Quantitative assessments involved whole-liver T1 estimates, volumes, PDFF and the ratio of |T1<sub>liver</sub>-T1<sub>sat</sub>|/T1<sub>liver</sub>. A five-point Likert scale was used for qualitative assessments.<h4>Results</h4>The ratios of |T1<sub>liver</sub>-T1<sub>sat</sub>|/T1 <sub>liver</sub> in FB T1 mapping were higher than those of BH T1 mapping in the overall population and obese group (<i>p</i> both < 0.05). No significant difference was found in liver T1 estimates in patients with BH failure between sequences (<i>p</i>＞0.05). FB T1 mapping outperformed BH in artifact scores for the obese group (<i>p</i> = 0.015). Of the 3 groups, the obese group exhibited the greatest amount of artifact in BH FSPGR T1 mapping (<i>p</i> < 0.05). The FB T1 mapping demonstrated superior performance in minimizing artifacts in the lower liver region in persons with BH failure [4 (4, 5) vs. 3 (3, 4), <i>p</i> < 0.001].<h4>Conclusion</h4>For overweight and obese patients with difficulty holding their breath during abdominal scanning, VFA FB radial stack-of-stars FSPGR T1 mapping served as a complementary and alternative method to BH sequence.
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