Sleep research article
Performance of six screening scores for obstructive sleep apnoea in an African population: findings from the BeSAS cross-sectional study.
Authors: Wachinou AP , Diallo BD , Totah T , Solelhac G , Berger M , Fosto P , Amidou S , Fiogbe AA , Marques-Vidal P , Agodokpessi G , Houinato D , Johnson RC , Preux PM , Heinzer R
One-line summary
A sleep science research article on Performance of six screening scores for obstructive sleep apnoea in an African population: findings from the BeSAS cross-sectional study..
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中文解读
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Original abstract
<h4>Background</h4>A screening tool for obstructive sleep apnoea (OSA) is useful in low-income countries where it may be difficult to access sleep recordings. The objective of this study was to assess the performance of six screening scores compared with objective sleep recording.<h4>Methods</h4>This analysis is based on the "Benin Sleep and Society" (BeSAS) study, in which respiratory polygraphy (PG) was performed using a type III device and OSA screening questionnaires (STOP, STOP-Bang, Berlin, NOSAS [≥8 and ≥ 5), No-Apnea, GOAL) were administered to participants. PG-defined OSA severity categories were defined according to the apnoea-hypopnoea index (AHI): mild (AHI 5 to <15/h), moderate (AHI 15 to <30/h) or severe (AHI ≥30/h), and these were compared to score findings.<h4>Results</h4>A total of 1810 subjects (mean age 45.4 ± 14.6 years; 64.3% women) were included. For moderate to severe OSA, the area under the receiver operating characteristic curve was greatest for GOAL and No-Apnea (0.70, CI 0.67-0.73; 0.70, CI 0.68-0.73), followed by NoSAS<sub>5</sub> (0.69, CI 0.65-0.73). The highest sensitivity values were for NoSAS<sub>5</sub> (0.73, CI 0.67-0.79), No-Apnea (0.72, CI 0.66-0.78), and GOAL (0.69, CI 0.67-0.79), while NoSAS<sub>8</sub> had the highest specificity (0.91, CI 0.90-0.93), followed by Berlin (0.88, CI 0.87-0.90) and GOAL (0.71, CI 0.69-0.73). All scores performed poorly with respect to the positive predictive value (PPV), which was highest with NoSAS<sub>8</sub> (0.38, CI 0.31-0.44).<h4>Conclusion</h4>Although overall performance was modest for all instruments, NoSAS<sub>8</sub> showed the highest PPV among the evaluated scores. These findings suggest that NoSAS<sub>8</sub> may be a useful option to support OSA risk stratification in resource-constrained settings, but should be interpreted with caution.
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